WHAT DOES IL-2 THERAPY FOR MELANOMA MEAN?

It really is well recognized that IL-2 is a pleiotropic cytokine positioned at the crossroads of T cell activation and regulation. Therefore, it really is critical to engineer an IL-2 molecule which is biased towards effector cells bearing the intermediate affinity receptor, such as naïve and memory CD8+ T cells and NK cells, compared to Treg cell